Levagen is a clinically studied form of palmitoylethanolamide (PEA) that supports joint health and a healthy joint inflammation response. Levagen utilizes the endocannabinoid system, potentiating its actions at CB1, CB2, and GPR55 receptors, and TRPV1 channels for supporting joint function, reducing joint stiffness and providing joint comfort.
PEA is an interesting anti-inflammatory therapeutic substance and might also hold great promise for the treatment of a number of (auto)immune disorders, including inflammatory bowel disease and inflammatory diseases of the CNS.?
As PEA clearly plays a fundamental role as a protective and restorative modulating lipid precursor, its clinical role is currently further evaluated in a variety of disorders such as inflammatory bowel disorder, central neuropathic pain in spinal cord disorders, various eye disorders such as glaucoma and degenerative retinal disorders, multiple sclerosis, amyotrophic lateral sclerosis, and Alzheimer's disease.?
In individuals, PEA helps reduce pain intensity, since (PEA) has been reported to down-modulate mast cell activation and to control glial cell behaviours.? Patients who take PEA supplements may have reduced pain intensity when compared to those who don’t take the supplement. Patients who struggled with back pain tended to notice significant relief when using this compound.? Studies have shown that PEA helps improve pelvic pain. In one study conducted on women, taking PEA in a period of 6 months helped improve not only pain but also sexual function symptoms, thereby improving the overall quality of life.?
PEA also displays promising effects when given to patients with stroke. In the recovery outcomes of the patients having a stroke, PEA was able to improve brain status and cognitive skills when compared to those patients who did not receive the supplement.?
What Makes Levagen®+ Unique To Other PEA Supplements
Levagen®+ is efficacious and safe. It is backed by human clinical studies with interesting anti-inflammatory and analgesic properties. Its unique mechanism of action for reducing pain / induce relaxation (similar to CBD) sets it apart from other PEA supplements on the market. It is an exceptional alternative to NSAIDS and cannabidiol.
Clinically, there are no adverse effects reported with this exact type of PEA preparation. But most importantly, in a parallel, double-blind, bioavailability study researchers aimed to determine whether the use of a Lipid-Based Drug Delivery System, LipiSperse®, can be successfully used to improve the bioavailability of palmitoylethanolamide. Standard PEA supplements are insoluble in a watery GI tract.
To evaluate the uniqueness and advantage of this technology, a study involved 28 healthy male and female volunteers over 18 years old.
The treatment regimen involved:
Group 1: Levagen+TM (300 mg PEA with, LipiSperse®)
Group 2: Standard PEA formulation (300 mg PEA).
The outcome measures were:
Change in the uptake of PEA over a 4 hour period.
The safety profile was also assessed.
Levagen®+ formulation significantly increased plasma PEA concentration by approximately 1.8x that of standard palmitoylethanolamide.
Levagen®+ can have the same efficacy, if not better, at lower dosages compared to standard PEA. Better value for money for the consumer. Its unique delivery system (LipiSperse® technology) ensures high bioavailability and functionality, requiring lower dosages / High loading.
Furthermore, Levagen®+ is banned-substance tested (NSF/LGC) and it is made in Australia.
However, unlike CBD, Levagen®+ is self-affirmed GRAS (generally recognized as safe), making it not only a safer alternative to CBD and nonsteroidal anti-inflammatory drugs, but a completely legal one too!
MOVE FREELY, LIVE FREELY
Are you having a hard time getting out of bed in the morning because of a stiff back? Do you need a hand to get up off the couch due to bad knees? Is it hard to get in and out of the car? As you get older, aches and pains start coming out of every part of your body!
Start moving freely again with Levagen. As a complete joint pain supplement, it helps repair cartilage, boost joint mobility, increase joint flexibility, support joint structure and protect joint tissue. Suitable for anyone with joint pain, joint inflammation or stiff joints.
It’s time to take back your youth. BE WELL & ACTIVE
How many times a day do you feel discomfort when doing things you once did with no issues? Is your daily exercise routine out of the question due to unforeseen knee pain? When is the last time you did things around the house without any issues?
You are not alone! An estimated 91.2 million adults have been medically diagnosed with some form of arthritis or symptoms related to it. Scientifically formulated to be the most complete treatment to ease joint pain and discomfort while enhancing range of motion, Levagen has been clinically researched to be an advanced joint repair complex designed to provide fast joint relief by easing joint aches and soreness.
Get back to living an active lifestyle with Levagen.
Our clinically studied ingredients are formulated in FDA-registered, GMP compliant facilities, made right here in the USA
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